Recorded Webinar with Dr. Roxana Ursea: Clinical Applications of Amniotic Membrane in Ocular Surface Disease
Recorded on Tuesday, October 24, 2017
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Watch the recorded webinar to hear Dr. Roxana Ursea, clinical associate professor of ophthalmology at the University of Arizona Department of Ophthalmology and Visual Sciences, discuss how the amniotic membrane can help heal ocular surface disease, its clinical significance, and data from various clinical applications.
Amniotic membrane is the innermost layer of the placenta. It contains a single layer of epithelial cells, a thick basement membrane, and a stroma. The basement membrane supports epithelial cell migration, adhesion, and differentiation and inhibits epithelial cell apoptosis. The stroma is avascular and rich in growth factors and protease inhibitor, which are biologically active factors that facilitate regenerative healing. Amniotic membrane stabilizes the ocular surface, exhibits strong anti-inflammatory properties, promotes healing without scarring, and supports stem cell expansion. In patients with moderate to severe dry eye, cryopreserved amniotic membrane plays a role in corneal nerve regeneration and restores corneal nerve integrity.
During this webinar, Dr. Roxana Ursea discusses how the amniotic membrane can be used as a biological bandage for superficial epithelial defects or as a permanent graft for deeper defects, including stromal defects, post-infectious ulcers, recurrent erosions/endothelial basement membrane dystrophy, small corneal perforations, inflammatory conditions, and chemical burns. She also covers how it’s especially beneficial in ocular surface reconstruction cases as well as in selected post-surgical procedures.
You will learn about the:
- Role of amniotic membrane in promoting regenerative healing
- Clinical significance of amniotic membrane and the rationale for its use
- Science behind amniotic membrane use and its ocular indications and outcomes, including data from clinical cases
- Pearls and pitfalls in using the amniotic membrane products in your practice
Roxana Ursea, MD, discusses the background and significance the amniotic membrane plays in healing a variety of ocular surface diseases and will share data for how to best utilize these clinical applications.
Dr. Ursea is a clinical associate professor of ophthalmology at the University of Arizona Department of Ophthalmology and Visual Sciences. After graduating from medical school summum cum laude in Bucharest, Romania, Dr. Ursea completed a residency in internal medicine. In 1990, she pursued further post-graduate training in the United States with fellowships in vascular biology and high-frequency ultrasound ophthalmology at Cornell University Medical College.
After completing her residency in ophthalmology at New York-Presbyterian Hospital/Weill Cornell and University of Maryland in Baltimore, Dr. Ursea expanded her clinical expertise with specialized training in uveitis and ocular immunology at the National Eye Institute of NIH in Bethesda, Maryland. She completed a second fellowship in cornea, external diseases, and refractive surgery at the University of California in San Diego.
Dr. Ursea is active in many professional organizations and has published in major peer-reviewed journals. She is a recognized national and international expert in ocular imaging, in particular, high-frequency ultrasound, and has received numerous awards, including the American Academy of Ophthalmology’s Achievement Award and the University of Arizona’s prestigious Vernon and Virginia Furrow Award for Excellence in Teaching Clinical Sciences.
Her clinical interests include keratoconus, laser vision correction, and challenging uveitis cases while her research interests include exploring new applications of high frequency ultrasound and new therapeutic modalities for anterior segment disorders. She has an active clinical and surgical practice at Northwest Medical Center in Tucson, Arizona.
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