New contracts, services and acquisitions drive earnings and revenue growth in first quarter of fiscal 2010;

Conference call scheduled for today at 10:00 a.m. EST, 9:00 a.m. CST

LENEXA, KS November 3, 2009- Mediware Information Systems, Inc. (Nasdaq: MEDW), a provider of comprehensive healthcare software solutions for blood, medication and performance management, reported total revenue for the first quarter of the 2010 fiscal year of $10.7M, a 9 percent increase from the $9.8M reported in the comparable quarter in fiscal 2009. Net income for the quarter increased to $619,000, or 8 cents per fully diluted share, a 267 percent increase over the $218,000, or 3 cents per fully diluted share reported in the comparable quarter of fiscal 2009.

Commenting on the quarter, Mediware president and chief executive officer, Thomas Mann, said: “Good performance in the first quarter is incredibly important to a successful year. I’m very pleased with the continued progress in our growth programs, particularly the integration and financial contributions of our three strategic acquisitions.

“Our Blood Center Technologies group, formed following the acquisition of IMS, has continued to sell our robust LifeTrak software to new blood centers. This product clearly has market momentum and Blood Center Technologies is a key contributor to our increasing base of recurring revenue.

“JAC has continued its strong performance from last year with key new contracts in the first quarter. Its ePrescribing module is the market leader in the UK and we’re optimistic this growth will continue.

“Our BloodSafe suite of products is also gaining traction with both new contracts as well as customers going live on this innovative system. Having just met with many of our customers at a large industry tradeshow, I see that these organizations have moved through the awareness cycle and have included these products in their budgets. I’m confident sales of these products will accelerate.”

• Earnings for the quarter increased 267% over the 3-cents reported last year.
• Performance represents 5th consecutive quarterly increase for earnings and revenue.
• Operating income increased to $1.0 million, compared to $212k last year.
• Cash increased by $1M during the quarter.

• The BloodSafe product went live at a key multi-facility healthcare system in the southeast and was sold to another prominent healthcare organization in the Northwest.
• Medication management contracts for two large organizations were expanded to include additional Mediware product modules, MediMAR at one and MediREC at the other.
• The addition of 3 new facilities for the Ascend product line, including one of which is the result of our agreement with a new business partner.
• Sale of the Insight Performance Management product to another prestigious IDN-affiliated hospital in the Southeast.
• New JAC contracts were executed with three NHS hospital trusts for the electronic prescribing and medication administration module.

“I’m very pleased with our performance in the first quarter,” stated Mr. Mann. “I believe the strategic moves we are making through new products, acquisitions and business relationships will continue to contribute to our growth in the future.”

The Company will host a teleconference call at 10:00 am Eastern Time (9:00 am Central Time) that day to discuss the results. There will be a question-and-answer session directly following the presentation of the results.

Participants are encouraged to register for the call in advance online by going to http://www.directeventreg.com/registration/event/38213233. Participants without online access may call toll-free (888) 869-1189 or (706) 643-5902 to register for the call. The conference ID is 38213233. Phone registrants should call in at least five minutes prior to the scheduled start of the call.

A replay of the call will be available after the call’s completion for 5 days at 800-642-1687 (direct dial 706-645-9291). The conference ID is 38213233. After 5 days, the replay will be available on the company’s web site: www.mediware.com.